Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies.

Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies.

Muscarinic ACh receptors mediate complicated and clinically vital results within the striatum. To higher perceive the roles of the completely different muscarinic receptor subtypes (m1-m4), now we have decided the mobile and subcellular distribution of the m1-m4 receptor proteins within the rat neostriatum utilizing subtype-specific antibodies and avidin-biotin-peroxidase immunocytochemistry for mild and electron microscopy. m1

The distribution of tau in the mammalian central nervous system.

The distribution of tau in the mammalian central nervous system.

We now have decided the biochemical and immunocytochemical localization of the heterogeneous microtubule-associated protein tau utilizing a monoclonal antibody that binds to the entire tau polypeptides in each bovine and rat mind. Utilizing immunoblot assays and aggressive enzyme-linked immunosorbent assays, now we have proven tau to be extra considerable in bovine white matter extracts and microtubules than in extracts