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Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies.

Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies.

Posted on June 25, 2021April 8, 2021 By Valerie Holmes

Muscarinic ACh receptors mediate complicated and clinically vital results within the striatum. To higher perceive the roles of the completely different muscarinic receptor subtypes (m1-m4), now we have decided the mobile and subcellular distribution of the m1-m4 receptor proteins within the rat neostriatum utilizing subtype-specific antibodies and avidin-biotin-peroxidase immunocytochemistry for mild and electron microscopy. m1 receptor protein is expressed in 78% of neurons and is enriched in spiny dendrites and at postsynaptic densities. A small variety of m1-immunoreactive axon terminals had been noticed, all forming asymmetrical synapses.

About 2.5% of striatal neurons specific m2 receptor protein with response product evident, by mild microscopy in scattered giant oval neurons with enfolded nuclei and lengthy aspiny dendrites. By electron microscopy, m2 immunocytochemistry labeled somata, aspiny dendrites, and lots of axon terminals. Most axon terminals containing m2 make symmetrical synapses with somata, and dendritic shafts and spines. As well as, many m2-immunoreactive axon terminals fashioned asymmetrical synapses with spines or dendrites. m3 receptor protein was not evident in somata by mild microscopy however was current in a definite inhabitants of small-caliber spiny dendrites in addition to in axon terminals forming asymmetrical synapses with spines.

m4 receptor protein was heterogeneously distributed within the neostriatum and localized to 44% of striatal cells. m4-positive neurons had the ultrastructural options of medium spiny neurons with response product notably concentrated in spines, typically at postsynaptic densities. Axon terminals containing m4 kind asymmetrical synapses, primarily with spines. These findings point out that the muscarinic receptor proteins happen in distinct populations of striatal neurons; that the receptor proteins focus postsynaptically at synapses, together with many thought of to be noncholinergic; that m2 is the predominant muscarinic autoreceptor within the striatum; and that every receptor subtype could also be a presynaptic heteroceptor within the striatum modulating extrinsic striatal afferents.

The amyloid speculation of Alzheimer’s illness at 25 years.

Regardless of persevering with debate concerning the amyloid β-protein (or Aβ speculation, new strains of proof from laboratories and clinics worldwide assist the idea that an imbalance between manufacturing and clearance of Aβ42 and associated Aβ peptides is a really early, typically initiating think about Alzheimer’s illness (AD). Affirmation that presenilin is the catalytic web site of γ-secretase has offered a linchpin: all dominant mutations inflicting early-onset AD happen both within the substrate (amyloid precursor protein, APP) or the protease (presenilin) of the response that generates Aβ.

Duplication of the wild-type APP gene in Down’s syndrome results in Aβ deposits within the teenagers, adopted by microgliosis, astrocytosis, and neurofibrillary tangles typical of AD Apolipoprotein E4, which predisposes to AD in>> 40% of instances, has been discovered to impair Aβ clearance from the mind. Soluble oligomers of Aβ42 remoted from AD sufferers’ brains can lower synapse quantity, inhibit long-term potentiation, and improve long-term synaptic despair in rodent hippocampus, and injecting them into wholesome rats impairs reminiscence. The human oligomers additionally induce hyperphosphorylation of tau at AD-relevant epitopes and trigger neuritic dystrophy in cultured neurons.

Crossing human APP with human tau transgenic mice enhances tau-positive neurotoxicity. In people, new research present that low cerebrospinal fluid (CSF) Aβ42 and amyloid-PET positivity precede different AD manifestations by a few years. Most significantly, latest trials of three completely different Aβ antibodies (solanezumab, crenezumab, and aducanumab) have steered a slowing of cognitive decline in submit hoc analyses of gentle AD topics. Though many elements contribute to AD pathogenesis, Aβ dyshomeostasis has emerged as essentially the most extensively validated and compelling therapeutic goal.

Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies.

Particular proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

Apoptosis is a morphologically and biochemically distinct type of cell dying that happens below a wide range of physiological and pathological situations. Within the current research, the proteolytic cleavage of poly(ADP-ribose) polymerase (pADPRp) throughout the course of chemotherapy-induced apoptosis was examined. Remedy of HL-60 human leukemia cells with the topoisomerase II-directed anticancer agent etoposide resulted in morphological adjustments attribute of apoptosis. Endonucleolytic degradation of DNA to generate nucleosomal fragments occurred concurrently.

Western blotting with epitope-specific monoclonal and polyclonal antibodies revealed that these attribute apoptotic adjustments had been accompanied by early, quantitative cleavage of the M(r) 116,000 pADPRp polypeptide to an M(r) roughly 25,000 fragment containing the amino-terminal DNA-binding area of pADPRp and an M(r) roughly 85,000 fragment containing the automodification and catalytic domains. Exercise blotting revealed that the M(r) roughly 85,000 fragment retained basal pADPRp exercise however was not activated by exogenous nicked DNA. Comparable cleavage of pADPRp was noticed after publicity of HL-60 cells to a wide range of chemotherapeutic brokers together with cis-diaminedichloroplatinum(II), colcemid, 1-beta-D-arabinofuranosylcytosine, and methotrexate; to gamma-irradiation

or to the protein synthesis inhibitors puromycin or cycloheximide. Comparable adjustments had been noticed in MDA-MB-468 human breast most cancers cells handled with trifluorothymidine or 5-fluoro-2′-deoxyuridine and in gamma-irradiated or glucocorticoid-treated rat thymocytes present process apoptosis. Remedy with a number of compounds (tosyl-L-lysine chloromethyl ketone, tosyl-L-phenylalanine chloromethyl ketone, N-ethylmaleimide, iodoacetamide) prevented each the proteolytic cleavage of pADPRp and the internucleosomal fragmentation of DNA. The outcomes recommend that proteolytic cleavage of pADPRp, along with being an early marker of chemotherapy-induced apoptosis, may replicate extra widespread proteolysis that may be a vital biochemical occasion early throughout the means of physiological cell dying.

Myosin Heavy Chain Monoclonal Antibody

ABM40058-003ml Abbkine 0.03ml
EUR 158
Description: A monoclonal antibody for detection of Myosin Heavy Chain from Human, Mouse, Rat, Fruit Fly, Nematode. This Myosin Heavy Chain antibody is for IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Myosin Heavy Chain Monoclonal Antibody

ABM40058-01ml Abbkine 0.1ml
EUR 289
Description: A monoclonal antibody for detection of Myosin Heavy Chain from Human, Mouse, Rat, Fruit Fly, Nematode. This Myosin Heavy Chain antibody is for IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Myosin Heavy Chain Monoclonal Antibody

ABM40058-02ml Abbkine 0.2ml
EUR 414
Description: A monoclonal antibody for detection of Myosin Heavy Chain from Human, Mouse, Rat, Fruit Fly, Nematode. This Myosin Heavy Chain antibody is for IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Myosin Heavy Chain (Mhc) Antibody

abx235172-100ug Abbexa 100 ug
EUR 551

Anti-Myosin Heavy Chain antibody

STJ96960 St John's Laboratory 200 µl
EUR 197
Description: Mouse monoclonal to Myosin Heavy Chain.

Myosin Heavy Chain Monoclonal Antibody

EM1058-100ul ELK Biotech 100ul
EUR 279
Description: A Mouse Monoclonal antibody against Myosin Heavy Chain from Human/ Mouse/ Rat/ Fruit Fly/ Nematode. This antibody is tested and validated for IHC, IF

Myosin Heavy Chain Monoclonal Antibody

EM1058-50ul ELK Biotech 50ul
EUR 207
Description: A Mouse Monoclonal antibody against Myosin Heavy Chain from Human/ Mouse/ Rat/ Fruit Fly/ Nematode. This antibody is tested and validated for IHC, IF

Myosin Heavy Chain protein

30-1187 Fitzgerald 100 ug
EUR 839
Description: Purified native Human Myosin Heavy Chain protein

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx130543 Abbexa
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx126210 Abbexa
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx113944 Abbexa
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Myosin Heavy Chain 2 (MYH2) Antibody

20-abx113946 Abbexa
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx103932 Abbexa
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Myosin Heavy Chain 4 (MYH4) Antibody

20-abx103933 Abbexa
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Myosin Heavy Chain 4 (MYH4) Antibody

20-abx103934 Abbexa
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Myosin Heavy Chain 2 (MYH2) Antibody

20-abx104340 Abbexa
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Myosin Heavy Chain 16 (MYH16) Antibody

20-abx102273 Abbexa
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Myosin Heavy Chain 4 (MYH4) Antibody

20-abx014616 Abbexa
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx001267 Abbexa
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Myosin Heavy Chain 2 (MYH2) Antibody

20-abx002613 Abbexa
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Anti-MYH14/Myosin Heavy Chain Antibody

A04528 BosterBio 100ul
EUR 397
Description: Rabbit Polyclonal MYH14/Myosin Heavy Chain Antibody. Validated in WB and tested in Human.

Myosin Heavy Chain 4 (MYH4) Antibody

20-abx323087 Abbexa
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Myosin Heavy Chain 15 (MYH15) Antibody

20-abx323947 Abbexa
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Myosin Heavy Chain 2 (MYH2) Antibody

20-abx217005 Abbexa
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Myosin Heavy Chain 15 (MYH15) Antibody

abx217027-100ug Abbexa 100 ug
EUR 439

Myosin Heavy Chain 11 (MYH11) Antibody

abx238026-100ug Abbexa 100 ug
EUR 481

Myosin Heavy Chain 11 (MYH11) Antibody

abx238027-100ug Abbexa 100 ug
EUR 509

Myosin Heavy Chain 11 (MYH11) Antibody

abx238028-100ug Abbexa 100 ug
EUR 509

Myosin Heavy Chain 11 (MYH11) Antibody

abx238029-100ug Abbexa 100 ug
EUR 551

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx214496 Abbexa
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx214949 Abbexa
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx177672 Abbexa
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Myosin Heavy Chain 2 (MYH2) Antibody

20-abx177673 Abbexa
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Myosin Heavy Chain 2 (MYH2) Antibody

20-abx177674 Abbexa
  • EUR 1135.00
  • EUR 551.00
  • 1 mg
  • 200 ug

Myosin Heavy Chain 4 (MYH4) Antibody

20-abx177675 Abbexa
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx173675 Abbexa
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Myosin Heavy Chain 2 (MYH2) Antibody

20-abx173676 Abbexa
  • EUR 787.00
  • EUR 411.00
  • 1 mg
  • 200 ug

Myosin Heavy Chain 4 (MYH4) Antibody

20-abx173678 Abbexa
  • EUR 342.00
  • EUR 857.00
  • EUR 439.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Monoclonal antibody for Myosin heavy chain

SMC-258D Stressmarq 0.1ml
EUR 314
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is not conjugated.

Monoclonal antibody for Myosin heavy chain

SMC-258D-A390 Stressmarq 0.1ml
EUR 361
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with ATTO 390.

Monoclonal antibody for Myosin heavy chain

SMC-258D-A488 Stressmarq 0.1ml
EUR 360
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with ATTO 488.

Monoclonal antibody for Myosin heavy chain

SMC-258D-A565 Stressmarq 0.1ml
EUR 360
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with ATTO 565.

Monoclonal antibody for Myosin heavy chain

SMC-258D-A594 Stressmarq 0.1ml
EUR 360
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with ATTO 594.

Monoclonal antibody for Myosin heavy chain

SMC-258D-A633 Stressmarq 0.1ml
EUR 360
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with ATTO 633.

Monoclonal antibody for Myosin heavy chain

SMC-258D-A655 Stressmarq 0.1ml
EUR 360
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with ATTO 655.

Monoclonal antibody for Myosin heavy chain

SMC-258D-A680 Stressmarq 0.1ml
EUR 360
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with ATTO 680.

Monoclonal antibody for Myosin heavy chain

SMC-258D-A700 Stressmarq 0.1ml
EUR 360
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with ATTO 700.

Monoclonal antibody for Myosin heavy chain

SMC-258D-ALP Stressmarq 0.1ml
EUR 355
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with Alkaline Phosphatase.

Monoclonal antibody for Myosin heavy chain

SMC-258D-APC Stressmarq 0.1ml
EUR 359
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with APC.

Monoclonal antibody for Myosin heavy chain

SMC-258D-APCCY7 Stressmarq 0.1ml
EUR 432
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with APC/Cy7.

Monoclonal antibody for Myosin heavy chain

SMC-258D-BI Stressmarq 0.1ml
EUR 357
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with Biotin.

Monoclonal antibody for Myosin heavy chain

SMC-258D-DY350 Stressmarq 0.1ml
EUR 436
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with Dylight 350.

Monoclonal antibody for Myosin heavy chain

SMC-258D-DY405 Stressmarq 0.1ml
EUR 412
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with Dylight 405.

Monoclonal antibody for Myosin heavy chain

SMC-258D-DY488 Stressmarq 0.1ml
EUR 393
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with Dylight 488.

Monoclonal antibody for Myosin heavy chain

SMC-258D-DY594 Stressmarq 0.1ml
EUR 397
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with Dylight 594.

Monoclonal antibody for Myosin heavy chain

SMC-258D-DY633 Stressmarq 0.1ml
EUR 387
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with Dylight 633.

Monoclonal antibody for Myosin heavy chain

SMC-258D-FITC Stressmarq 0.1ml
EUR 353
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with FITC.

Monoclonal antibody for Myosin heavy chain

SMC-258D-HRP Stressmarq 0.1ml
EUR 349
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with HRP.

Monoclonal antibody for Myosin heavy chain

SMC-258D-P594 Stressmarq 0.1ml
EUR 367
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with PE/ATTO 594.

Monoclonal antibody for Myosin heavy chain

SMC-258D-PCP Stressmarq 0.1ml
EUR 359
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with PerCP.

Monoclonal antibody for Myosin heavy chain

SMC-258D-RPE Stressmarq 0.1ml
EUR 358
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with RPE.

Monoclonal antibody for Myosin heavy chain

SMC-258D-STR Stressmarq 0.1ml
EUR 359
Description: A monoclonal antibody from clone 11C2 against Human | Mouse Myosin heavy chain. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human Myosin Heavy Chain. The antibody is tested and validated for IHC, ICC/IF assays with the following recommended dilutions: IHC (1:100), ICC/IF (1:100). This MAb for Myosin heavy chain is conjugated with Streptavidin.

Myosin Heavy Chain Mouse Monoclonal Antibody

38013-100ul SAB 100ul
EUR 252

Myosin Heavy Chain Mouse Monoclonal Antibody

38013-50ul SAB 50ul
EUR 187

Myosin Heavy Chain 4 (MYH4) Antibody

abx330335-100ul Abbexa 100 ul
EUR 425

Myosin Heavy Chain 4 (MYH4) Antibody

20-abx334199 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Myosin Heavy Chain 11 (MYH11) Antibody

20-abx334295 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Myosin heavy chain recombinant monoclonal antibody

A5558 Bimake 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Myosin heavy chain for WB, IHC,ELISA

anti-Myosin Heavy Chain (11C2)

LF-MA20351 Abfrontier 100 ug
EUR 354
Description: Mouse monoclonal to Myosin Heavy Chain

anti-heavy chain cardiac Myosin

YF-PA24193 Abfrontier 50 ul
EUR 334
Description: Mouse polyclonal to heavy chain cardiac Myosin

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNCA0893-250 Biotium 250uL
EUR 383
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), APC conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNCAP0893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNCAP0893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC810893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF680R conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC810893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF680R conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNCB0893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), Biotin conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNCB0893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), Biotin conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC550893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF555 conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC550893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF555 conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC430893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF543 conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC430893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF543 conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC470893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF647 conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC470893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF647 conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC880893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF488A conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC880893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF488A conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC940893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF594 conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC940893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF594 conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNCP0893-250 Biotium 250uL
EUR 383
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), PerCP conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC040893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF405S conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC040893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF405S conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC050893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF405M conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC050893-500 Biotium 500uL
EUR 544
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF405M conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNCR0893-250 Biotium 250uL
EUR 383
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), RPE conjugate, Concentration: 0.1mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNUB0893-100 Biotium 100uL
EUR 209
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), Concentration: 0.2mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNUB0893-500 Biotium 500uL
EUR 458
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), Concentration: 0.2mg/mL

Myosin Smooth Muscle Heavy Chain(SMMS-1) Antibody

BNC680893-100 Biotium 100uL
EUR 199
Description: Primary antibody against Myosin, Smooth Muscle Heavy Chain(SMMS-1), CF568 conjugate, Concentration: 0.1mg/mL

Artificial Abeta oligomers of the identical dimension gave equivalent punctate binding, which was extremely selective for explicit neurons. Picture evaluation by confocal double-label immunofluorescence established that >90% of the punctate oligomer binding websites colocalized with the synaptic marker PSD-95 (postsynaptic density protein 95). Synaptic binding was accompanied by ectopic induction of Arc, a synaptic immediate-early gene, the overexpression of which has been linked to dysfunctional studying. Outcomes recommend the speculation that concentrating on and practical disruption of explicit synapses by Abeta oligomers might present a molecular foundation for the precise lack of reminiscence operate in early AD.

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May 2022
M T W T F S S
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9101112131415
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23242526272829
3031  
« Jan    

Categories

  • Antibodies
  • Blog
  • Cultrex
  • Default
  • Dot
  • EIA
  • electrophoresis
  • Exosomes
  • Gels
  • Goat
  • HRP
  • Isotypes
  • NATtrol
  • Particles
  • Rabbit
  • Species

Recent Posts

  • Mycoplasma pneumoniae Recombinants
  • Canis lupus familiaris Recombinants
  • Cricetulus griseus Recombinants
  • Heat-labile UDG
  • Immunemed HANTA RAPID
May 2022
M T W T F S S
 1
2345678
9101112131415
16171819202122
23242526272829
3031  
« Jan    

Categories

  • Antibodies
  • Blog
  • Cultrex
  • Default
  • Dot
  • EIA
  • electrophoresis
  • Exosomes
  • Gels
  • Goat
  • HRP
  • Isotypes
  • NATtrol
  • Particles
  • Rabbit
  • Species

Recent Posts

  • Mycoplasma pneumoniae Recombinants
  • Canis lupus familiaris Recombinants
  • Cricetulus griseus Recombinants
  • Heat-labile UDG
  • Immunemed HANTA RAPID

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