Within the current examine, a set of three monoclonal antibodies is described, every of which acknowledges cells of the monocyte-macrophage lineage within the rat. The tissue distribution, specifically in lymphoid organs, of every of the three monoclonals is decided by immunoenzyme histochemistry on cryostat sections, in addition to on cell suspensions. Outcomes present that ED1 acknowledges a cytoplasmic antigen in monocytes and in most macrophages, free and stuck. ED2 and ED3 acknowledge membrane antigens of tissue macrophages, discriminating between distinct subpopulations of macrophages, every with a attribute localization within the compartments of lymphoid organs. No different cell sorts besides cells of the mononuclear phagocyte system are optimistic for any of the three monoclonals.
Attainable relations between the macrophages acknowledged by this set of monoclonals and dendritic cells are mentioned. Hybrid myeloma cell strains secreting monoclonal antibodies to tubulin have been ready utilizing rat myelomas and spleen cells from rats immunized with yeast tubulin. A comparability between the outcomes obtained with the rat myeloma Y3-Ag 1.2.3., which secretes a light-weight chain, and a brand new line, YB2/O, which doesn’t, reveals that they’re each glorious parental strains and that the second produces hybrids with no myeloma chain elements.
The antitubulin antibodies within the serum of rats bearing two of the hybrid myeloma tumors gave titers of as much as 1:10(6) from which giant quantities of monoclonal antibodies could possibly be simply purified. They acknowledged tubulin from yeast in addition to from birds and mammals. The 2 antibodies gave clear immunofluorescent staining of yeast mitotic spindles in addition to the interphase microtubule community of tissue tradition cells. Some distinction within the sample of immunofluorescence staining of yeast cells and nuclei was noticed between the 2 antibodies. The purified antibodies could possibly be conjugated to colloidal gold particles and used for direct labeling of yeast microtubules for electron microscopy.
Sclerostin antibody therapy will increase bone formation, bone mass, and bone energy in a rat mannequin of postmenopausal osteoporosis.
The event of bone-rebuilding anabolic brokers for potential use within the therapy of bone loss circumstances, akin to osteoporosis, has been a long-standing aim. Genetic research in people and mice have proven that the secreted protein sclerostin is a key destructive regulator of bone formation, though the magnitude and extent of sclerostin’s position within the management of bone formation within the getting older skeleton continues to be unclear. To review this unexplored space of sclerostin biology and to evaluate the pharmacologic results of sclerostin inhibition, we used a cell tradition mannequin of bone formation to establish a sclerostin neutralizing monoclonal antibody (Scl-AbII) for testing in an aged ovariectomized rat mannequin of postmenopausal osteoporosis.
Six-month-old feminine rats have been ovariectomized and left untreated for 1 yr to permit for important estrogen deficiency-induced bone loss, at which level Scl-AbII was administered for five wk. Scl-AbII therapy in these animals had sturdy anabolic results, with marked will increase in bone formation on trabecular, periosteal, endocortical, and intracortical surfaces. This not solely resulted in full reversal, at a number of skeletal websites, of the 1 yr of estrogen deficiency-induced bone loss, but in addition additional elevated bone mass and bone energy to ranges larger than these present in non-ovariectomized management rats.
Taken collectively, these preclinical outcomes set up sclerostin’s position as a pivotal destructive regulator of bone formation within the getting older skeleton and, moreover, recommend that antibody-mediated inhibition of sclerostin represents a promising new therapeutic method for the anabolic therapy of bone-related problems, akin to postmenopausal osteoporosis. On the onset of the illness, monoclonal antibodies in opposition to a myelin/oligodendrocyte glycoprotein (MOG) have been injected intravenously.
Two subsets of rat T lymphocytes outlined with monoclonal antibodies.
A brand new monoclonal mouse antibody that acknowledges a subset of rat peripheral T cells has been ready by immunizing mice with rat thymocyte glycoprotein. This antibody, designated MRC OX 8, labels all peripheral T cells which are unlabeled by the beforehand described W3/25 monoclonal antibody. No peripheral T cells have been discovered that sure each antibodies, however, in distinction, 90% of thymocytes have been doubly labeled. Thoracic duct lymphocytes of congenitally athymic nude rats weren’t labeled by both antibody, however the spleens of such animals contained each W3/25+ cells and MRC OX 8+ cells.
These splenocyte subpopulations didn’t overlap. Utilizing the fluorescence-activated cell sorter to isolate cells binding MRC OX Eight antibody, the phenotype of T cells mediating numerous T cell capabilities was established. Combining the current outcomes with these printed beforehand, it’s proven that the cells offering assist for antibody responses and people mediating graft-vs.-host reactions are phenotypically W3/25+ MRC OX 8-. Then again, parental T cells that suppress antibody formation in F1 hosts have been recognized as W3/25- MRC OX 8+. The connection between the rat T cell subsets outlined by these antibodies and people within the mouse recognized by the Ly sequence of alloantibodies is mentioned and a comparability made between teh rat W3/25+ subset and a lately recognized human T cell subset.
 Antibody) Peptidylprolyl Isomerase D (PPID) Antibody |
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| 20-abx114383 | Abbexa |
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 Antibody) Peptidylprolyl Isomerase F (PPIF) Antibody |
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| 20-abx114385 | Abbexa |
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 Antibody) Peptidylprolyl Isomerase E (PPIE) Antibody |
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| 20-abx102681 | Abbexa |
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Peptidylprolyl Isomerase E (PPIE) Antibody |
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| 20-abx102682 | Abbexa |
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Peptidylprolyl Isomerase F (PPIF) Antibody |
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| 20-abx102683 | Abbexa |
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Peptidylprolyl Isomerase F (PPIF) Antibody |
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| 20-abx102684 | Abbexa |
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 Antibody) Peptidylprolyl Isomerase H (PPIH) Antibody |
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| abx036170-100ug | Abbexa | 100 ug | EUR 391 |
Peptidylprolyl Isomerase E (PPIE) Antibody |
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| abx036194-100ug | Abbexa | 100 ug | EUR 391 |
Peptidylprolyl Isomerase D (PPID) Antibody |
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| abx036719-100ug | Abbexa | 100 ug | EUR 391 |
 Antibody) Peptidylprolyl Isomerase G (PPIG) Antibody |
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| 20-abx000715 | Abbexa |
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Peptidylprolyl Isomerase G (PPIG) Antibody |
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| abx431741-200ul | Abbexa | 200 ul | EUR 384 |
Peptidylprolyl Isomerase D (PPID) Antibody |
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| abx430156-200ul | Abbexa | 200 ul | EUR 384 |
Peptidylprolyl Isomerase G (PPIG) Antibody |
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| abx236677-100ug | Abbexa | 100 ug | EUR 509 |
Peptidylprolyl Isomerase H (PPIH) Antibody |
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| abx236678-100ug | Abbexa | 100 ug | EUR 481 |
 Antibody) Peptidylprolyl Isomerase C (PPIC) Antibody |
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| 20-abx173989 | Abbexa |
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 Antibody (HRP)) Peptidylprolyl Isomerase H (PPIH) Antibody (HRP) |
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| 20-abx304924 | Abbexa |
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 Antibody (FITC)) Peptidylprolyl Isomerase H (PPIH) Antibody (FITC) |
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| 20-abx304925 | Abbexa |
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 Antibody (Biotin)) Peptidylprolyl Isomerase H (PPIH) Antibody (Biotin) |
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| 20-abx304926 | Abbexa |
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-Like 2 Antibody) Peptidylprolyl Isomerase (Cyclophilin)-Like 2 Antibody |
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| 20-abx114375 | Abbexa |
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-Like 3 Antibody) Peptidylprolyl Isomerase (Cyclophilin)-Like 3 Antibody |
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| 20-abx114376 | Abbexa |
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-Like 4 Antibody) Peptidylprolyl Isomerase (Cyclophilin)-Like 4 Antibody |
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| 20-abx114377 | Abbexa |
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-Like 5 Antibody) Peptidylprolyl Isomerase (Cyclophilin)-Like 5 Antibody |
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| 20-abx114378 | Abbexa |
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-Like 6 Antibody) Peptidylprolyl Isomerase (Cyclophilin)-Like 6 Antibody |
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| 20-abx114379 | Abbexa |
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 Antibody) Peptidylprolyl Isomerase A (Cyclophilin A) Antibody |
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| 20-abx114380 | Abbexa |
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 Antibody) Peptidylprolyl Isomerase B (Cyclophilin B) Antibody |
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| 20-abx114381 | Abbexa |
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 Antibody) Peptidylprolyl Isomerase C (Cyclophilin C) Antibody |
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| 20-abx114382 | Abbexa |
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 Antibody) Peptidylprolyl Isomerase G (Cyclophilin G) Antibody |
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| 20-abx114386 | Abbexa |
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 Antibody) Peptidylprolyl Isomerase-Like 5 (PPIL5) Antibody |
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| abx037351-100ug | Abbexa | 100 ug | EUR 391 |
Peptidylprolyl Isomerase-Like 5 (PPIL5) Antibody |
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| abx030021-400ul | Abbexa | 400 ul | EUR 523 |
Peptidylprolyl Isomerase-Like 5 (PPIL5) Antibody |
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| abx030021-80l | Abbexa | 80 µl | EUR 286 |
 Antibody) Peptidylprolyl Isomerase/Cyclophilin Like 1 (PPIL1) Antibody |
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| abx122629-100ug | Abbexa | 100 ug | EUR 391 |
-Like 1 (PPIL1) Antibody) Peptidylprolyl Isomerase (Cyclophilin)-Like 1 (PPIL1) Antibody |
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| 20-abx114374 | Abbexa |
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 (PPIH) Antibody) Peptidylprolyl Isomerase H (Cyclophilin H) (PPIH) Antibody |
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| 20-abx114387 | Abbexa |
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 Antibody) Peptidylprolyl Isomerase/Cyclophilin Like 2 (PPIL2) Antibody |
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| abx036009-100ug | Abbexa | 100 ug | EUR 391 |
 Antibody) Peptidylprolyl Isomerase/Cyclophilin Like 3 (PPIL3) Antibody |
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| abx036265-100ug | Abbexa | 100 ug | EUR 391 |
 Antibody) Peptidylprolyl Isomerase/Cyclophilin Like 4 (PPIL4) Antibody |
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| abx037728-100ug | Abbexa | 100 ug | EUR 391 |
Peptidylprolyl Isomerase/Cyclophilin Like 1 (PPIL1) Antibody |
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| abx029043-400ul | Abbexa | 400 ul | EUR 523 |
Peptidylprolyl Isomerase/Cyclophilin Like 1 (PPIL1) Antibody |
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| abx029043-80l | Abbexa | 80 µl | EUR 286 |
Peptidylprolyl Isomerase/Cyclophilin Like 3 (PPIL3) Antibody |
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| abx029263-400ul | Abbexa | 400 ul | EUR 523 |
Peptidylprolyl Isomerase/Cyclophilin Like 3 (PPIL3) Antibody |
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| abx029263-80l | Abbexa | 80 µl | EUR 286 |
 Antibody) Peptidylprolyl Isomerase/Cyclophilin Like 6 (PPIL6) Antibody |
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| abx029765-400ul | Abbexa | 400 ul | EUR 523 |
Peptidylprolyl Isomerase/Cyclophilin Like 6 (PPIL6) Antibody |
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| abx029765-80l | Abbexa | 80 µl | EUR 286 |
Peptidylprolyl Isomerase/Cyclophilin Like 2 (PPIL2) Antibody |
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| abx030105-400ul | Abbexa | 400 ul | EUR 523 |
Peptidylprolyl Isomerase/Cyclophilin Like 2 (PPIL2) Antibody |
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| abx030105-80l | Abbexa | 80 µl | EUR 286 |
Peptidylprolyl Isomerase/Cyclophilin Like 4 (PPIL4) Antibody |
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| abx030448-400ul | Abbexa | 400 ul | EUR 523 |
Peptidylprolyl Isomerase/Cyclophilin Like 4 (PPIL4) Antibody |
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| abx030448-80l | Abbexa | 80 µl | EUR 286 |
Peptidylprolyl Isomerase/Cyclophilin Like 3 (PPIL3) Antibody |
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| 20-abx310769 | Abbexa |
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Peptidylprolyl Isomerase/Cyclophilin Like 4 (PPIL4) Antibody |
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| 20-abx318408 | Abbexa |
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Peptidylprolyl Isomerase/Cyclophilin Like 2 (PPIL2) Antibody |
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| 20-abx321305 | Abbexa |
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Peptidylprolyl Isomerase/Cyclophilin Like 1 (PPIL1) Antibody |
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| abx236679-100ug | Abbexa | 100 ug | EUR 481 |
Peptidylprolyl Isomerase/Cyclophilin Like 2 (PPIL2) Antibody |
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| abx236680-100ug | Abbexa | 100 ug | EUR 481 |
Peptidylprolyl Isomerase/Cyclophilin Like 3 (PPIL3) Antibody |
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| abx236681-100ug | Abbexa | 100 ug | EUR 509 |
Peptidylprolyl Isomerase/Cyclophilin Like 4 (PPIL4) Antibody |
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| abx236682-100ug | Abbexa | 100 ug | EUR 509 |
Peptidylprolyl Isomerase/Cyclophilin Like 6 (PPIL6) Antibody |
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| abx236683-100ug | Abbexa | 100 ug | EUR 509 |
 Polyclonal Antibody (Human)) Peptidylprolyl Isomerase F (PPIF) Polyclonal Antibody (Human) |
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| 4-PAB549Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Peptidylprolyl Isomerase F (PPIF) |
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 Polyclonal Antibody (Human)) Peptidylprolyl Isomerase C (PPIC) Polyclonal Antibody (Human) |
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| 4-PAB636Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Peptidylprolyl Isomerase C (PPIC) |
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 Polyclonal Antibody (Human)) Peptidylprolyl Isomerase E (PPIE) Polyclonal Antibody (Human) |
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| 4-PAB493Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Peptidylprolyl Isomerase E (PPIE) |
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 Polyclonal Antibody (Mouse)) Peptidylprolyl Isomerase E (PPIE) Polyclonal Antibody (Mouse) |
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| 4-PAB493Mu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Peptidylprolyl Isomerase E (PPIE) |
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 Rabbit Polyclonal antibody Anti-CRBN |
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| Anti-CRBN | ImmunoStep | 50 µg | EUR 349 |
) Recombinant Peptidylprolyl Isomerase E (PPIE) |
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| 4-RPB493Hu01 | Cloud-Clone |
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Description: Recombinant Human Peptidylprolyl Isomerase E expressed in: E.coli |
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Recombinant Peptidylprolyl Isomerase E (PPIE) |
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| 4-RPB493Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Peptidylprolyl Isomerase E expressed in: E.coli |
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) Recombinant Peptidylprolyl Isomerase F (PPIF) |
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| 4-RPB549Hu01 | Cloud-Clone |
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Description: Recombinant Human Peptidylprolyl Isomerase F expressed in: E.coli |
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Recombinant Peptidylprolyl Isomerase F (PPIF) |
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| 4-RPB549Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Peptidylprolyl Isomerase F expressed in: E.coli |
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) Recombinant Peptidylprolyl Isomerase C (PPIC) |
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| 4-RPB636Hu01 | Cloud-Clone |
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Description: Recombinant Human Peptidylprolyl Isomerase C expressed in: E.coli |
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 Pig Peptidylprolyl Isomerase ELISA kit |
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| E07P0705-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Porcine Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Peptidylprolyl Isomerase ELISA kit |
|||
| E07P0705-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Porcine Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Peptidylprolyl Isomerase ELISA kit |
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| E07P0705-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Dog Peptidylprolyl Isomerase ELISA kit |
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| E08P0705-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Canine Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Peptidylprolyl Isomerase ELISA kit |
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| E08P0705-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Canine Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Peptidylprolyl Isomerase ELISA kit |
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| E08P0705-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Canine Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Rabbit Peptidylprolyl Isomerase ELISA kit |
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| E04P0705-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Rabbit Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Peptidylprolyl Isomerase ELISA kit |
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| E04P0705-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Rabbit Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Peptidylprolyl Isomerase ELISA kit |
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| E04P0705-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Goat Peptidylprolyl Isomerase ELISA kit |
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| E06P0705-192T | BlueGene | 192 tests | EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Goat Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Peptidylprolyl Isomerase ELISA kit |
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| E06P0705-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Goat Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Peptidylprolyl Isomerase ELISA kit |
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| E06P0705-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Goat Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Mouse Peptidylprolyl Isomerase ELISA kit |
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| E03P0705-192T | BlueGene | 192 tests | EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Peptidylprolyl Isomerase ELISA kit |
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| E03P0705-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Peptidylprolyl Isomerase ELISA kit |
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| E03P0705-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Rat Peptidylprolyl Isomerase ELISA kit |
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| E02P0705-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Rat Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Peptidylprolyl Isomerase ELISA kit |
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| E02P0705-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Rat Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Peptidylprolyl Isomerase ELISA kit |
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| E02P0705-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Rat Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Human Peptidylprolyl Isomerase ELISA kit |
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| E01P0705-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Human Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Peptidylprolyl Isomerase ELISA kit |
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| E01P0705-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Human Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Peptidylprolyl Isomerase ELISA kit |
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| E01P0705-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Human Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Monkey Peptidylprolyl Isomerase ELISA kit |
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| E09P0705-192T | BlueGene | 192 tests | EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey Peptidylprolyl Isomerase ELISA kit |
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| E09P0705-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey Peptidylprolyl Isomerase ELISA kit |
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| E09P0705-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Peptidylprolyl Isomerase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Antibody (HRP)) Peptidylprolyl Isomerase/Cyclophilin Like 4 (PPIL4) Antibody (HRP) |
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| 20-abx310155 | Abbexa |
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 Antibody (FITC)) Peptidylprolyl Isomerase/Cyclophilin Like 4 (PPIL4) Antibody (FITC) |
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| 20-abx310156 | Abbexa |
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 Antibody (Biotin)) Peptidylprolyl Isomerase/Cyclophilin Like 4 (PPIL4) Antibody (Biotin) |
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| 20-abx310157 | Abbexa |
|
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 Antibody (HRP)) Peptidylprolyl Isomerase/Cyclophilin Like 3 (PPIL3) Antibody (HRP) |
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| 20-abx310770 | Abbexa |
|
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 Antibody (FITC)) Peptidylprolyl Isomerase/Cyclophilin Like 3 (PPIL3) Antibody (FITC) |
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| 20-abx310771 | Abbexa |
|
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 Antibody (Biotin)) Peptidylprolyl Isomerase/Cyclophilin Like 3 (PPIL3) Antibody (Biotin) |
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| 20-abx310772 | Abbexa |
|
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On this examine the authors have developed a mannequin with which might be studied instantly the affect of circulating anti-myelin antibody on the medical and pathologic course of inflammatory T-cell-mediated experimental allergic encephalomyelitis (EAE) within the rat. EAE was induced by passive switch of both myelin primary protein (MBP)-activated spleen cells derived from sensitized donors or long-term-cultured MBP-specific T-cell strains. This antigen is uncovered on the floor of central nervous system myelin and oligodendrocytes. Intravenous injection of the antibody in the midst of T-cell-mediated switch EAE augmented the severity and period of medical indicators and resulted within the formation of enormous, confluent demyelinated plaques.
